Operating under the Ministry of Energy of the Republic of Uzbekistan, NIRES was established by Presidential Decree No. 5063 (April 2021) to advance renewable and hydrogen energy in Uzbekistan. The institute conducts fundamental and applied research, develops innovative technologies, and supports policy and regulatory frameworks for the sector.

Its structure includes dedicated centers for hydrogen energy research and laboratories for testing and certification of renewable energy technologies. NIRES actively collaborates with local and international scientific institutions, contributes to investment project development, and works to strengthen education-to-industry linkages in clean energy innovation.